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Right Flank Pain and Fever

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BACKGROUND
A 56-year-old man with history of hepatitis C and diabetes mellitus presents to the emergency department with right flank pain and subjective fevers of 2-3 days' duration. The patient describes his pain as mild in intensity but constant. It is nonradiating, with a pressure-like quality. The patient takes 20 units of neutral protamine hagedorn (NPH) insulin injected subcutaneously twice daily for his diabetes but states that his self-reported daily blood glucometer readings have been approximately 250-350 mg/dL for the past month.

On physical examination, vital signs are a blood pressure of 100/60 mm Hg, a heart rate of 96 beats per minute, a respiratory rate of 16 breaths per minute, and an oral temperature of 39.0°C. The cardiac and respiratory portions of the examination are unremarkable. The patient is noted to have tenderness in the right costovertebral angle. His abdominal examination is unremarkable for any tenderness to palpation, rebound, or guarding.

Clinically significant laboratory results include a WBC of 24.4 X 109/L, a blood urea nitrogen concentration of 71 mg/dL, a creatinine level of 5.4 mg/dL, and a serum glucose level 629 mg/dL. Urinalysis reveals cloudy urine with copious WBCs, a glucose concentration of 100 mg/dL, a protein concentration of 100 mg/dL, and large leukocyte esterase.

Renal ultrasonography is performed and reveals an abnormality of the right kidney (see Images 1-2). To further illustrate this abnormality, an abdominal CT scan was obtained (see Image 3). What is the diagnosis?
Hint
This condition most commonly occurs in patients with diabetes.
Authors: Pramod Gupta, MD, Staff Radiologist, Dallas VA Medical Center, Texas

Nahid Eshaghi, MD, Acting Chief of Radiology, Dallas VA Medical Center, Texas
eMedicine Editors:

Erik Schraga, MD, UCLA - Olive View Medical Center Residency, Department of Emergency Medicine, Olive View - UCLA Medical Center

Rick G. Kulkarni, MD, Assistant Professor, Yale School of Medicine, Section of Emergency Medicine, Department of Surgery, Attending Physician, Medical Director, Department of Emergency Services, Yale-New Haven Hospital


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