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I Can't Breathe

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BACKGROUND

A 40-year-old woman arrives at the emergency department with a markedly panicked appearance, screaming, "I can't breathe!" She is anxiously flailing her arms and appears tachypneic and pale. Six nurses are needed to obtain her vital signs and to place an intravenous (IV) line. The patient's heart rate is 120 beats per minute (bpm) with a blood pressure of 200/88 mm Hg, a respiratory rate of 50 breaths per minute, and oxygen saturation of 79% with the patient breathing room air. She is unable to cooperate with history taking and physical examination, and she repeatedly removes her oxygen mask and monitoring equipment. She is intubated on an emergency basis by using rapid-sequence induction.

After the patient is adequately sedated, physical examination is possible. The ventilator is set on assist-control mode at a rate of 16 bpm, tidal volume of 600 mL, positive end-expiratory pressure (PEEP) of 5 cm H2O, and a fraction of inspired oxygen (FiO2) of 100%. Her vital signs include a rectal temperature of 37.1°C with a heart rate of 110 bpm, ventilator-assisted respiratory rate of 16 breaths per minute, blood pressure of 183/100 mm Hg, and O2 saturation of 100%. Her pupils are equal, round, and reactive to light. She has no jugular venous distension or tracheal shift. Her heart rate is a regular rhythm with no appreciable murmurs, rubs, or gallops. She has coarse breath sounds with bibasilar rales. Abdominal examination reveals linea nigra, and moderate distension is noted, but palpation yields softness without any masses. She has no lower-extremity edema or rashes.

The patient's husband arrives and provides additional history. They had a baby by means of normal spontaneous vaginal delivery 2 months ago with no complications. Three days ago, the patient began having shortness of breath, which was worst at night and when she was lying flat or exerting herself. She has been using an over-the-counter epinephrine inhaler (0.22 mg, Primatene Mist), with no improvement. She has no notable medical history of asthma, chronic obstructive pulmonary disease (COPD), or other respiratory problems. He denies any knowledge of drug or alcohol use.

An ECG shows sinus tachycardia with frequent premature ventricular contractions (PVCs). The patient has no ST-segment or T-wave changes and no S1Q3T3 pattern.

A portable postintubation chest radiograph is obtained (see Image 1). Bedside abdominal and cardiac ultrasonographies are performed in the emergency department. The sonogram of her abdomen shows no free fluid and a nongravid uterus. Images 2-4 are her cardiac sonograms.

What is the diagnosis and treatment?
Hint
The patient had no symptoms before she became pregnant.
Authors: Adam Landman, MD, MS, MIS,
UCLA/Olive View-UCLA Emergency Medicine Residency Program,
Los Angeles, Calif

Gelareh Zargaraff, MD,
UCLA/Olive View-UCLA Emergency Medicine Residency Program,
Los Angeles, Calif

Timothy Jang, MD,
Attending Physician,
Department of Emergency Medicine,
Director of Emergency Ultrasound,
Olive View -UCLA Medical Center,
Assistant Professor of Medicine,
David Geffen School of Medicine at UCLA
eMedicine Editor: Erik D. Schraga, MD,
Department of Emergency Medicine,
Kaiser Permanente,
Santa Clara Medical Center, Calif


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