
		• The American Association of Clinical Endocrinologists medical guidelines for the management of diabetes mellitus: the AACE system of intensive diabetes self-management--2002 update. • Standards of medical care in diabetes. I. Classification and diagnosis. • Screening for retinopathy in the pediatric patient with type 1 diabetes mellitus.


		• Diabetes Mellitus, Type 1 • Diabetic Ketoacidosis • Infant of Diabetic Mother • View All Type 1 Diabetes Mellitus Articles


		• Taking Diabetes to School (video) • Effects of insulin deficiency • View All Type 1 Diabetes Mellitus Multimedia Files


		• Diabetes • Diabetic Foot Care • Diabetic Ketoacidosis • Insulin Reaction


		• Body Mass Index • Ideal Body Weight for Females (lbs) • Ideal Body Weight for Males (lbs)

Type 1 Diabetes Mellitus Resource Center

Diabetes Mellitus, Type 1

Endocrinology

Type 1 DM is a catabolic disorder in which circulating insulin is very low or absent, plasma glucagon is elevated, and the pancreatic beta cells fail to respond to all insulin-secretory stimuli. Patients need exogenous insulin to reverse this catabolic condition, prevent ketosis, decrease hyperglucagonemia, and normalize lipid and protein metabolism.

Diabetic Ketoacidosis

Endocrinology

Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes. DKA mainly occurs in patients with type 1 diabetes, but it is not uncommon in some patients with type 2 diabetes. DKA is defined clinically as an acute state of severe uncontrolled diabetes that requires emergency treatment with insulin and intravenous fluids.

Infant of Diabetic Mother

Pediatrics

Diabetes has long been associated with maternal and perinatal morbidity and mortality. Before the discovery of insulin in 1921, diabetic women rarely reached reproductive age or survived pregnancy. In fact, pregnancy termination was recommended routinely for pregnant diabetic patients because of high mortality rates.

Diabetes Resource Center

Type 2 Diabetes Mellitus Resource Center

Klein R, Moss SE, Sinaiko AR, Zinman B, Gardiner R, Suissa S, et al. The Relation of Ambulatory Blood Pressure and Pulse Rate to Retinopathy in Type 1 Diabetes Mellitus The Renin-Angiotensin System Study. Ophthalmology . 2006 Sep 21; [Epub ahead of print].

Sittiwet C, Gylling H, Hallikainen M, Pihlajamaki J, Moilanen L, Laaksonen DE, et al. Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of type 1 diabetes: The effect of improved glycemic control. Atherosclerosis. 2006 Sep 21; [Epub ahead of print].

Agras PI, Kinik ST, Cengiz N, Baskin E. Type 1 diabetes mellitus associated with nephrotic syndrome. J Pediatr Endocrinol Metab. 2006 Aug;19(8):1045-8.

Rachmiel M, Bloch O, Bistritzer Z, Weintrob N, Ofan R, Bloch K, et al. Clinical characteristics and diabetes associated autoantibodies in patients with both type 1 diabetes mellitus and asthma. J Pediatr Endocrinol Metab. 2006 Aug;19(8):1001-6.

Mayhan WG, Arrick DM, Sharpe GM, Patel KP, Sun H. Inhibition of NAD(P)H Oxidase Alleviates Impaired NOS-dependent Responses of Pial Arterioles in Type 1 Diabetes Mellitus. Microcirculation. 2006 Oct-Nov;13(7):567-75.

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